Lipid Peroxidation
Definition
Lipid peroxidation is a process where free radicals attack lipids containing carbon-carbon double bond(s), particularly in cell membranes, which can lead to cell damage.
Scientific / Technical Definition
Lipid peroxidation refers to the oxidative degradation of lipids, typically involving polyunsaturated fatty acids in cellular membranes. This process is initiated by free radicals and results in the formation of malondialdehyde and other reactive species that can induce cell damage and inflammation.
Benefits
- Understanding lipid peroxidation helps in assessing oxidative stress in the body.
- It can aid in the development of antioxidant therapies.
Examples
- Increased levels of lipid peroxidation are found in fried and processed foods.
- Oils rich in polyunsaturated fatty acids, such as those in fish, can be susceptible to peroxidation if not properly stored.
Additional Information
- Effects: Lipid peroxidation can damage cell membranes, leading to loss of cell integrity, apoptosis, and can play a role in conditions such as atherosclerosis and neurodegenerative diseases.
References
Last updated: 10/19/2024