Cholesterol Biosynthesis

Definition

Cholesterol biosynthesis is the process by which the body makes cholesterol, a type of fat essential for building cell membranes and producing hormones.

Scientific / Technical Definition

Cholesterol biosynthesis is a complex, multistep process involving over 30 enzymes that converts acetyl-CoA into cholesterol. This metabolic pathway occurs mainly in the liver and involves the mevalonate pathway as a key component.

Benefits

• Essential for cell membrane structure
• Vital for the synthesis of steroid hormones
• Important in the production of bile acids which aid in digestion
• Contributes to the formation of vitamin D

Examples

• Endogenous production in the liver
• Minor production in the intestines

Additional Information

• Importance: Cholesterol biosynthesis is crucial as it provides the body with cholesterol needed for essential biological processes, even when dietary intake is low.

Related Terms

• Cholesterol Metabolism
• Lipid Synthesis
• Steroid Hormones
• Lipid Metabolism

References

• Cholesterol Biosynthesis Pathway: An Overview
• The Role of Cholesterol in the Body