Celiac Disease
Definition
Celiac disease is a chronic autoimmune disorder where the ingestion of gluten leads to damage in the small intestine.
Scientific / Technical Definition
Celiac disease is an autoimmune condition that occurs in genetically predisposed individuals where the ingestion of gluten—a protein found in wheat, barley, and rye—elicits an immune-mediated enteropathy characterized by inflammation and villous atrophy of the small intestinal mucosa.
Benefits
- Early diagnosis and treatment by adhering to a strict gluten-free diet can improve symptoms and prevent potential complications associated with untreated Celiac disease.
Examples
- Wheat, barley, and rye products are common sources of gluten that must be avoided by individuals with Celiac disease.
- Alternative gluten-free grains include rice, quinoa, and millet.
Additional Information
- Known Issues: Undiagnosed or untreated Celiac disease can lead to additional health problems including malnutrition, osteoporosis, infertility, and neurological diseases.
- Side Effects: Common manifestations include gastrointestinal symptoms like diarrhea, bloating, and pain, as well as non-gastrointestinal symptoms like anemia, skin rash, and fatigue.
Related Terms
Last updated: 10/19/2024