Anaphylaxis

Definition

Anaphylaxis is a severe and potentially life-threatening allergic reaction that can occur quickly after exposure to an allergen, such as certain foods or insect stings.

Scientific / Technical Definition

Anaphylaxis is an acute, systemic allergic reaction resulting from the sudden release of mediators from mast cells and basophils. It can involve multiple organ systems, leading to a drop in blood pressure, airway obstruction, and potentially fatal cardiovascular collapse if not treated promptly with epinephrine.

Benefits

Examples

• Peanut allergy leading to anaphylactic shock
• Shellfish allergy resulting in anaphylaxis
• Bee sting causing anaphylaxis

Additional Information

• sideEffects: Symptoms of anaphylaxis may include difficulty breathing, hives, swelling, a drop in blood pressure, and gastrointestinal symptoms. Immediate treatment with epinephrine is crucial.

Related Terms

• Allergy
• Food Intolerance
• Histamine
• Epinephrine

References

• Guidelines for the diagnosis and management of food allergy in the United States: Report of the NIAID-sponsored expert panel
• Anaphylaxis: Guidelines from the European Academy of Allergy and Clinical Immunology