Acetyl-CoA

Definition

Acetyl-CoA is a molecule that helps cells produce energy by entering the Krebs cycle, a process that happens in the mitochondria.

Scientific / Technical Definition

Acetyl-CoA is an important metabolic intermediate formed from the breakdown of carbohydrates, fats, and proteins. It carries the acetyl group for its subsequent entry into the Krebs cycle (citric acid cycle), enabling the production of ATP, the energy currency of the cell. It is also crucial in fatty acid synthesis and cholesterol metabolism.

Benefits

• Essential for energy production in the body.
• Plays a role in fat and carbohydrate metabolism.
• Contributes to the synthesis of certain neurotransmitters.

Examples

• Carbohydrate metabolism pathways
• Fatty acid breakdown
• Amino acid catabolism

Additional Information

• Importance: Acetyl-CoA is crucial for energy metabolism and acts as a central molecule in several biochemical pathways for both energy production and biosynthesis.

Related Terms

• ATP
• Metabolism
• Mitochondria
• Catabolism

References

• Acetyl-CoA: Biosynthesis, Functions and Role in Disease
• Role of Acetyl-CoA in Metabolism: A Double-edged Sword