Insulin Resistance

Definition

Insulin resistance is a condition where the body's cells become less responsive to the hormone insulin, leading to higher blood sugar levels.

Scientific / Technical Definition

Insulin resistance is a pathological condition in which cells fail to respond effectively to insulin, a hormone produced by the pancreas that regulates blood glucose levels. This condition often leads to higher circulating levels of glucose and can contribute to the development of type 2 diabetes and other metabolic disorders.

Benefits

• Addressing insulin resistance can help improve blood sugar control.
• Reducing insulin resistance may decrease the risk of type 2 diabetes.
• It can also aid in weight management and reduce the risk of cardiovascular disease.

Examples

• Insulin resistance is often managed with lifestyle interventions such as a balanced diet and regular physical activity.
• Whole foods like vegetables, fruits, lean proteins, and whole grains can help improve insulin sensitivity.

Additional Information

• Effects: This condition affects glucose uptake in cells, leading to elevated blood sugar levels. Over time, it can lead to increased production of insulin by the pancreas and potentially, beta-cell exhaustion.

Related Terms

• Diabetes
• Blood Sugar
• Metabolic Syndrome
• Type 2 Diabetes

References

• Insulin Resistance and Prediabetes
• Insulin Resistance: Practice Essentials, Background, Pathophysiology