Resistin

Definition

Resistin is a hormone produced by adipose (fat) tissue that is believed to play a role in obesity and insulin resistance.

Scientific / Technical Definition

Resistin is a cysteine-rich polypeptide hormone secreted by adipocytes in rodents and by immune and epithelial cells in humans. It is involved in the regulation of glucose homeostasis and has been implicated in various metabolic processes and inflammatory pathways that can affect insulin resistance.

Benefits

• Potentially involved in signaling processes that regulate energy metabolism.
• May have a role in modulating inflammatory responses.

Examples

• Resistin itself is not consumed from foods, but is produced by the body, primarily in fat cells.

Additional Information

• Effects: Resistin is implicated in insulin resistance, which is a precursor to type 2 diabetes. It also influences inflammation and has been studied for its role in cardiovascular diseases.

Related Terms

• Adiponectin
• Leptin
• Insulin resistance
• Cytokines

References

• The Role of Resistin in Obesity, Insulin Resistance, and Inflammation
• Resistin: an Inflammatory Cytokine