Caloric Restriction

Definition

Caloric restriction is a dietary regimen that reduces calorie intake without malnutrition, often used to improve health and potentially extend lifespan.

Scientific / Technical Definition

Caloric restriction involves reducing the average daily caloric intake below typical levels, without being associated with malnutrition or affecting the consumption of essential nutrients. It is known to alter several biological pathways, including metabolism and stress responses, which may contribute to enhanced longevity and reduced risk of age-related diseases.

Benefits

• May extend lifespan and delay aging
• Can improve metabolic health and insulin sensitivity
• Might reduce risk factors for chronic diseases such as cardiovascular diseases and type 2 diabetes
• May improve markers of inflammation and oxidative stress

Examples

• Reducing daily caloric intake by 20-30% while maintaining nutrient balance
• Implementing fasting protocols with limited calorie consumption on certain days

Additional Information

• Known issues: Prolonged or excessive caloric restriction can lead to malnutrition, loss of muscle mass, and impaired immune function if not managed properly.

Related Terms

• Intermittent Fasting
• Metabolic Rate
• Aging
• Longevity
• Metabolic Health

References

• The Calorie Restriction (CR) Paradigm: A Novel Intervention to Reduce Morbidity and Mortality
• Caloric Restriction and Aging: Review of the Effects on Life Span and Function